|
週次 |
日期 |
單元主題 |
|
第1週 |
3/05 |
啟洋: Metascape provides a biologist-oriented resource for the analysis of systems-level datasets.
NATURE COMMUNICATIONS | (2019) 10:1523
宇暄: CCL5 mediates target-kinase independent resistance to FLT3 inhibitors in FLT3-ITD-positive AML. Molecular Oncology (2020) doi:10.1002/1878-0261.12640 |
|
第2週 |
3/12 |
昂矩 Hematopoietic niche drives FLT3-ITD acute myeloid leukemia resistance to quizartinib via STAT5- and hypoxia-dependent upregulation of AXL. Haematologica (2019) 104(10):2017
家宏 N822K- or V560G-mutated KIT activation preferentially occurs in lipid rafts of the Golgi apparatus in leukemia cells. Cell Communication and Signaling (2019) 17:114 |
|
第3週 |
3/19 |
冠維--Atovaquone is active against AML by upregulating the integrated stress pathway and suppressing oxidative phosphorylation.
Blood advances (2019) 3:4215-4227
高煜--HDAC11 deficiency disrupts oncogene-induced
hematopoiesis in myeloproliferative neoplasms.
Blood. 2020;135(3):191-207
|
|
第4週 |
3/26 |
Lab meeting |
|
第5週 |
4/02 |
清明節 |
|
第6週 |
4/09 |
昂矩 Combined inhibition of Notch and FLT3 produces synergistic
cytotoxic effects in FLT3/ITD+ acute myeloid leukemia
Signal Transduction and Targeted Therapy (2020) 5:21
家宏 Homoharringtonine deregulates MYC transcriptional expression by directly binding NF-κB repressing factor
PNAS February 5, 2019 116 (6) 2220-2225
|
|
第7週 |
4/16 |
啟洋、宇暄 |
|
第8週 |
4/23 |
冠維、高煜 |
|
第9週 |
4/30 |
Lab meeting |
|
第10週 |
5/07 |
啟洋、宇暄 |
|
第11週 |
5/14 |
昂矩、家宏 |
|
第12週 |
5/21 |
冠維、高煜 |
|
第13週 |
5/28 |
啟洋、宇暄 |
|
第14週 |
6/04 |
Lab meeting |
|
第15週 |
6/11 |
昂矩、家宏 |
|
第16週 |
6/18 |
冠維、高煜 |